Cardiomyopathy refers to changes in the heart muscle. These changes prevent part or all of the heart from contracting normally.
There are three types of cardiomyopathy. The types are based on the physical changes that occur in the heart:
Dilated cardiomyopathy. The damaged heart muscle stretches out of shape. The heart becomes enlarged. It loses its ability to pump blood effectively. This eventually leads to heart failure.
Risk factors for dilated cardiomyopathy include:
High blood pressure
Prolonged, excessive alcohol use
Myocarditis (heart muscle inflammation)
Untreated thyroid disorders
Inherited genetic diseases
Disorders in which the heart muscle is overloaded with iron or amyloid protein
Radiation and chemotherapy treatments
Hypertrophic cardiomyopathy. The muscular heart wall thickens abnormally. As a result, the heart muscle cannot relax fully. As a result, the heart does not fill up with as much blood as in a healthy heart. So the heart has less blood to pump out to the body. There is another problem with hypertrophic cardiomyopathy, as well. The heart muscle wall can become so thickened that it blocks the flow of blood out of the heart. Both of these problems can lead to heart failure.
Restrictive cardiomyopathy. Various diseases can cause substances to be deposited where they do not belong: in the heart muscle. This causes the heart's muscular walls to become so rigid that the heart cannot expand to fill up with all the blood that is returning from the body. The result is that the heart does not have as much blood to pump as the body needs.
The symptoms of cardiomyopathy vary by type.
Dilated cardiomyopathy. Symptoms can include:
Shortness of breath, especially during exertion
Fatigue
Difficulty breathing while lying down
Leg swelling
Palpitations
Chest pain
Hypertrophic cardiomyopathy. Symptoms, when they occur, are usually the same as the symptoms of dilated cardiomyopathy. Sometimes, the first symptom may be fainting or even sudden death. The condition also can cause chest pain, usually during exercise.
Restrictive cardiomyopathy. Fluid accumulates in the legs and abdomen. This condition also can cause shortness of breath, especially during exertion.
Your doctor will review your medical history.
He or she will ask about:
Your family's history of heart disease
Any family members whose death was sudden and unexplained
Specific circumstances that trigger your heart-related symptoms
Your doctor will examine you, paying special attention to your heart.
This will be followed by:
An electrocardiogram (EKG). This test records the electrical activity of your heart.
A chest X-ray
Blood tests
An echocardiogram. This test uses sounds waves to create a picture of the heart at work.
You may also need other tests.
Dilated cardiomyopathy sometimes can be reversed if it is caused by a treatable condition.
Most cases of hypertrophic and restrictive cardiomyopathy are persistent. They can get worse over time.
The best way to prevent cardiomyopathy is to prevent the diseases that cause it.
Know your risk factors for coronary artery disease. Modify those risks early in life.
You can reduce your risk for coronary artery disease by:
Keeping blood pressure normal. Eat a diet rich in vegetables and fruits. Take medication as needed.
Drinking no more than two alcoholic beverages per day. Do not drink alcohol at all if you are at high risk of dilated cardiomyopathy.
If you have any family members with inherited cardiomyopathy, contact your doctor for an evaluation.
The treatment of cardiomyopathy depends on its cause. Here are some of the more common treatments:
Medications that prolong life in people with dilated cardiomyopathy.
Angiotensin-converting enzyme (ACE) inhibitors
Angiotensin receptor blockers
Beta-blockers
Aldosterone receptor antagonists
Drugs that improve the symptoms of heart failure in dilated cardiomyopathy.
Diuretics
ACE inhibitors
Angiotensin receptor blockers
Digoxin
Drugs that help to relax the heart muscle in hypertrophic cardiomyopathy.
Beta-blockers
Verapamil, a calcium-channel blocker drug
Antiarrhythmic drugs to correct abnormal heart rhythms.
A pacemaker or an implantable defibrillator to prevent fatal arrhythmias.
For patients with hypertrophic cardiomyopathy, blockage to the outflow of blood can sometimes be reduced. This is done by damaging part of the muscle between the two ventricles. This damage can be created at surgery or through a catheter.
A heart transplant may be necessary for patients whose poor heart function has become disabling or life threatening.
Call your doctor whenever you have any of the following symptoms:
Shortness of breath, with or without exertion
Difficulty breathing when you sleep or lie down
Fainting or light-headed spells
Palpitations
Leg swelling
Call your doctor immediately if you have chest pain. Call even if you think that you are too young to be having heart problems.
The outlook varies. It depends on the specific cause and severity of the cardiomyopathy.
The survival rate of people with most types has improved dramatically in the past decade. This is due to the increased number of treatments available.
American Heart Association (AHA)
7272 Greenville Ave.
Dallas, TX 75231
Toll-Free: 1-800-242-8721
http://www.americanheart.org/
National Heart, Lung, and Blood Institute (NHLBI)
P.O. Box 30105
Bethesda, MD 20824-0105
Phone: 301-592-8573
TTY: 240-629-3255
Fax: 240-629-3246
http://www.nhlbi.nih.gov/
American College of Cardiology
Heart House
2400 N Street NW
Washington, DC 20037
Phone: 202-375-6000
Toll-Free: 1-800-253-4636
http://www.acc.org/
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