Chrome 2001
.
Aetna Intelihealth InteliHealth Aetna Intelihealth Aetna Intelihealth
 
.
. .

   Advertisement
Carepass Ad Carepass Ad .
Chrome 2001
Chrome 2001
Health News Health News
.
More Pesticides Linked to Parkinson's Risk
February 03, 2014

 

MONDAY, Feb. 3, 2014 (HealthDay News) -- Researchers say they've identified a number of common pesticides that increase the risk of Parkinson's disease, and that they've also discovered that people's genes can affect their level of risk.

In a previous study, the University of California, Los Angeles team found that exposure to a banned pesticide called benomyl increases the risk of Parkinson's. In this new study, the researchers said they identified 11 other pesticides that increase that risk.

The pesticides inhibit an enzyme called "aldehyde dehydrogenase" (ALDH). It converts compounds called aldehydes -- which are highly toxic to brain cells that produce a chemical called dopamine -- into less harmful compounds.

A lack of dopamine causes the tremors, limb stiffness and loss of balance experienced by people with Parkinson's disease, according to the U.S. National Institute of Neurological Disorders and Stroke.

The UCLA researchers also found that people with a common variant of the ALDH2 gene are particularly vulnerable to these ALDH-inhibiting pesticides, according to a university news release. People with the variant are two to six times more likely to develop Parkinson's than those without the variant when exposed to the pesticides.

The levels at which the pesticides inhibit ALDH are much lower than those at which they are currently used, according to the study in the Feb. 5 online issue of the journal Neurology.

It included 360 people with Parkinson's and 816 people without the disease who lived in three central California counties with high levels of agricultural production.

"We were very surprised that so many pesticides inhibited ALDH and at quite low concentrations, concentrations that were way below what was needed for the pesticides to do their job," study author Jeff Bronstein, a professor of neurology and director of movement disorders at UCLA, said in the news release.

"These pesticides are pretty ubiquitous, and can be found in our food supply and are used in parks and golf courses and in pest control inside buildings and homes. So, this significantly broadens the number of people at risk," he added.

Although the study found an association between exposure to certain pesticides and higher risk of Parkinson's disease, it did not establish a cause-and-effect relationship.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about Parkinson's disease.
Copyright © 2014 HealthDay. All rights reserved.


SOURCE: University of California, Los Angeles, news release, Feb. 3, 2014...

InteliHealth
.
.
.
.
.
More News
InteliHealth .
.
General Health News
Today's News
Today In Health History
This Week In Health
Addiction News
Allergy News
Alzheimer's News
Arthritis News
Asthma News
Babies News
Breast Cancer News
Bronchitis News
Cancer News
Caregiving News
Cervical Cancer News
Children's Health News
Cholesterol News
Complementary & Alternative Medicine News
Dental/Oral Health News
Depression News
Diabetes News
Ear, Nose And Throat News
Environmental Health News
Eye News
Fitness News
Genetics News
Headache News
Health Policy News
Heart Attack News
Heart Failure News
Heart Health News
HIV/AIDS News
Infectious Diseases News
Influenza News
Lung Cancer News
Medication News
Men's Health News
Mental Health News
Multiple Sclerosis News
Nutrition News
Parkinson's News
Pregnancy News
Prevention News
Prostate Cancer News
Schizophrenia
Senior Health News
Sexual/Reproductive Health News
Sexual dysfunction
Sleep News
STDs News
Stroke News
Tobacco Cessation News
Weight Management News
Women's Health News
.
.
.
.
InteliHealth
    Print Printer-friendly format    
   
.  
This website is certified by Health On the Net Foundation. Click to verify.
.