Chrome 2001
.
Aetna Intelihealth InteliHealth Aetna Intelihealth Aetna Intelihealth
 
.
. .

   Advertisement
Carepass Ad Carepass Ad .
Chrome 2001
Chrome 2001
Health News Health News
.
Lab Mice Stressed Out By Men, But Not Women, Study Finds
April 28, 2014

 

MONDAY, April 28, 2014 (HealthDay News) -- The scent of male researchers, but not females, triggers stress in lab mice and rats -- stress that might alter the findings of experiments, a new study suggests.

Researchers at McGill University in Montreal, Canada, found that when men were in the lab, mice and rats had a stress response equal to being restrained for 15 minutes or being forced to swim for three minutes.

This stress made both male and female rodents less sensitive to pain and caused them to respond differently in behavioral tests, the team noted.

On the other hand, female researchers caused no stress reaction in the lab animals, according to the study published online April 28 in the journal Nature Methods.

In order to confirm that this stress response was related to scent, the researchers exposed mice to cotton T-shirts that had been worn by male and female researchers. The stress reaction was the same as that caused by the presence of researchers.

Further investigation revealed that the mice were stressed by chemicals called pheromones that men emit from their armpits at higher levels than women. Because all mammals share the same pheromones, these chemical signals alert the rodents that a male is nearby.

The findings could have real implications for rodent-based research everywhere, the Canadian team said. For one thing, they point out that scientists often find it difficult to replicate findings from animal research, which has led to concerns over the reliability of these studies.

However, "our findings suggest that one major reason for lack of replication of animal studies is the gender of the experimenter -- a factor that's not currently stated in the methods sections of published papers," study leader Robert Sorge, a psychology professor at the University of Alabama, Birmingham, said in a McGill University news release. He led the study while a postdoctoral fellow at McGill.

The "problem is easily solved by simple changes to experimental procedures," study senior author Jeffrey Mogil, a psychology professor at McGill, added in the news release.

"For example, since the effect of males' presence diminishes over time, the male experimenter can stay in the room with the animals before starting testing. At the very least, published papers should state the gender of the experimenter who performed the behavioral testing," Mogil said.

More information

The Hastings Center discusses animal research ethics.
Copyright © 2014 HealthDay. All rights reserved.


SOURCE: McGill University, news release, April 28, 2014...

InteliHealth
.
.
.
.
.
More News
InteliHealth .
.
General Health News
Today's News
Today In Health History
This Week In Health
Addiction News
Allergy News
Alzheimer's News
Arthritis News
Asthma News
Babies News
Breast Cancer News
Bronchitis News
Cancer News
Caregiving News
Cervical Cancer News
Children's Health News
Cholesterol News
Complementary & Alternative Medicine News
Dental/Oral Health News
Depression News
Diabetes News
Ear, Nose And Throat News
Environmental Health News
Eye News
Fitness News
Genetics News
Headache News
Health Policy News
Heart Attack News
Heart Failure News
Heart Health News
HIV/AIDS News
Infectious Diseases News
Influenza News
Lung Cancer News
Medication News
Men's Health News
Mental Health News
Multiple Sclerosis News
Nutrition News
Parkinson's News
Pregnancy News
Prevention News
Prostate Cancer News
Schizophrenia
Senior Health News
Sexual/Reproductive Health News
Sexual dysfunction
Sleep News
STDs News
Stroke News
Tobacco Cessation News
Weight Management News
Women's Health News
.
.
.
.
InteliHealth
    Print Printer-friendly format    
   
.  
This website is certified by Health On the Net Foundation. Click to verify.
.