Chrome 2001
.
Aetna Intelihealth InteliHealth Aetna Intelihealth Aetna Intelihealth
 
.
. .
.
Chrome 2001
Chrome 2001
Health News Health News
.
Drug May Lower Odds of Early Menopause in Breast Cancer Patients
May 30, 2014

 

FRIDAY, May 30, 2014 (HealthDay News) -- Adding a drug called goserelin to chemotherapy reduces the risk of early menopause in breast cancer patients and seems to improve survival, according to a new study.

Early menopause is one of the most upsetting side effects of chemotherapy among young breast cancer patients, the researchers noted.

The investigators found that adding goserelin to chemotherapy significantly reduced the risk of early menopause in breast cancer patients, and increased the chances that survivors could get pregnant and have a healthy baby later.

Goserelin (Zoladex) temporarily puts the ovaries "at rest" during chemotherapy, according to study senior author Dr. Kathy Albain, of Loyola University Medical Center in Maywood, Ill.

"We found that, in addition to reducing the risk of early menopause, and all of the symptoms that go along with menopause, goserelin was very safe and may even improve survival," she said in a Loyola news release. "I think these findings are going to change our clinical practice."

The study included 257 premenopausal women younger than 50 with early stage estrogen- or progesterone-receptor-negative breast cancers. The patients were randomly assigned to receive either standard chemotherapy or chemotherapy plus goserelin.

After two years, 45 percent of women in the chemotherapy-only group showed signs of early menopause, compared with just 20 percent of those in the chemo plus goserelin group. In addition, the authors noted, the pregnancy rate was 11 percent in the chemotherapy-only group and 21 percent in the goserelin group.

After four years, 89 percent of the women in the chemo plus goserelin group showed no signs or symptoms of cancer, compared with 78 percent of those in the chemotherapy-only group. Survival rates at four years were 92 percent in the goserelin group and 82 percent in the chemotherapy-only group, according to the report.

"Premenopausal women beginning chemotherapy for early breast cancer should consider this new option to prevent premature ovarian failure," the study authors concluded.

The findings are scheduled for presentation Saturday at the annual meeting of the American Society of Clinical Oncology (ASCO), held in Chicago. Research presented at meetings is considered preliminary until published in a peer-reviewed medical journal.

Goserelin is an injection drug that is similar to a natural hormone made by the body. It is approved by the U.S. Food and Drug Administration for treatment of prostate cancer, certain benign gynecological conditions and certain breast cancers.

More information

The U.S. National Library of Medicine has more about breast cancer.
Copyright © 2014 HealthDay. All rights reserved.


SOURCE: Loyola University, news release, May 30, 2014...

InteliHealth
.
.
.
.
.
More News
InteliHealth .
.
General Health News
Today's News
Today In Health History
This Week In Health
Addiction News
Allergy News
Alzheimer's News
Arthritis News
Asthma News
Babies News
Breast Cancer News
Bronchitis News
Cancer News
Cervical Cancer News
Children's Health News
Cholesterol News
Dental/Oral Health News
Depression News
Diabetes News
Ear, Nose And Throat News
Environmental Health News
Eye News
Fitness News
Genetics News
Headache News
Health Policy News
Heart Attack News
Heart Failure News
Heart Health News
HIV/AIDS News
Infectious Diseases News
Influenza News
Lung Cancer News
Medication News
Men's Health News
Mental Health News
Multiple Sclerosis News
Nutrition News
Parkinson's News
Pregnancy News
Prostate Cancer News
Schizophrenia
Senior Health News
Sexual/Reproductive Health News
Sexual dysfunction
Sleep News
STDs News
Stroke News
Tobacco Cessation News
Weight Management News
Women's Health News
.
.
.
.
InteliHealth
    Print Printer-friendly format    
   
.  
This website is certified by Health On the Net Foundation. Click to verify.
.