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General Medical Questions
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Question : I am 55 years old and had a hysterectomy at age 40. I have taken Estrace (1 tablet every other day) for the past 15 years.
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The Trusted Source
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Howard LeWine, M.D.

Howard LeWine, M.D., is chief editor of Internet Publishing, Harvard Health Publications. He is a clinical instructor of medicine at Harvard Medical School and Brigham and Women's Hospital. Dr. LeWine has been a primary care internist and teacher of internal medicine since 1978.

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April 27, 2012
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A:

Estrace is the brand name for the drug estradiol. It is a commonly used form of estrogen for women that:

  • Have premature menopause (menstrual periods stop before age 40)
  • Undergo a complete hysterectomy (removal of the ovaries and uterus) prior to natural menopause
  • Have menopausal symptoms, such as hot flashes and vaginal dryness

Estrace is available in 3 doses:

  • 0.5 mg
  • 1 mg
  • 2 mg

Your doctor’s advice is typical of what I and most other doctors recommend today. Until now, taking estrogen was appropriate for you.

It sounds like your Estrace dose is already pretty low since you take it every other day. That’s good. At this time, you should try to lower your dose if you can. Your goal is to find the lowest dose of Estrace to control menopausal symptoms. And then try to slowly decrease the dose until you can stop.

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