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Digestive Disorders
What is a normal liver enzyme count? My doctor said mine was borderline and wants me retested
What is a normal liver enzyme count? My doctor said mine was borderline and wants me retested
htmASKTHEDOCnormalliverenzyme
The two tests commonly called the "liver enzymes" are AST (aspartate transaminase or aspartate aminotransferase) and ALT (alanine transaminase or alanine aminotransferase).
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InteliHealth
2010-05-12
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Mary Pickett, M.D.
2012-05-12
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Q: What is a normal liver enzyme count? My doctor said mine was borderline and wants me retested
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The Trusted Source
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Mary Pickett, M.D.

Mary Pickett, M.D., is an Associate professor at Oregon Health & Science University where she is a primary care doctor for adults. She supervises and educates residents in the field of Internal Medicine, for outpatient and hospital care. She is a Lecturer for Harvard Medical School and a Senior Medical Editor for Harvard Health Publications.

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May 12, 2010
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A:

The two tests commonly called the "liver enzymes" are AST (aspartate transaminase or aspartate aminotransferase) and ALT (alanine transaminase or alanine aminotransferase).

The normal range for these tests varies from lab to lab. The high end of the range for each is around 40 U/L.

If liver cells are inflamed or damaged, the cells "leak" AST and ALT into the bloodstream. An elevated level can indicate liver damage.

Many things can cause your liver to become injured. Injuries large and small can cause AST and ALT changes. Some of the most common things to cause changes are:

  • Alcohol
  • Viral hepatitis
  • Other viruses (such as mononucleosis)
  • Many medications but particularly acetaminophen (Tylenol)
  • Fatty liver from obesity or diabetes

As it turns out, AST and ALT are also present in a few other tissues, particularly in muscle. Muscle injury can also cause an increase of the AST and ALT blood level.

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