Ask The Expert
April 18, 2011
There are some complications from using radiation therapy to treat Hodgkin's disease.
Most commonly, radiation is used in the chest area. This area, called the "mediastinum," is often involved with Hodgkin's disease.
The most common organ adversely affected by chest radiation is the thyroid gland. Radiation can damage thyroid cells that make thyroid hormone. This may lead to lower than normal blood levels of thyroid hormone (called hypothyroidism). Radiation also increases the risk of developing thyroid cancer.
People who have radiation to the chest need to be monitored for thyroid abnormalities for the rest of their lives.
Other complications from chest radiation include:
The risk of complications from radiation increases when the person is treated with chemotherapy and radiation therapy. The combination increases the risk of other cancers, including:
In the past, radiation was used on some tissues and organs in the abdomen. This could damage the kidney, leading to kidney failure and high blood pressure. This tends to be uncommon today, as radiation to this area is less frequently used.
Other side effects from chest radiation may include dry mouth, mouth sores and difficulty swallowing.