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Harvard Medical School
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General Medical Questions
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Q: Is there a liquid form of Zestril (or other medicines for high blood pressure)? I am unable to take pills.
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The Trusted Source
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Harold J. DeMonaco, M.S.

Harold J. DeMonaco, M.S., is senior analyst, Innovative Diagnostics and Therapeutics, and the chair of the Human Research Committee at the Massachusetts General Hospital. He is author of over 20 publications in the pharmacy and medical literature and routinely reviews manuscript submissions for eight medical journals.

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July 28, 2004
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A:

Zestril (also known as lisinopril) is not available in a liquid form. Some drugs have a special coating on the tablet that either protects the active ingredients from the acid in the stomach or protects the stomach from the effects of the drug. Coated tablets cannot be crushed. The good news for you is that Zestril comes as an uncoated tablet. That means that it can safely be crushed.

Your local pharmacy should be able to supply you with a pill crusher. There are many different brands available that range in price up to about $10 to $12. The crushed tablet can be mixed with a small amount (3 or 4 ounces) of water or apple juice just before you want to take it. Do not make it in advance, however. The Zestril powder probably won't dissolve completely, so make sure you rinse out the glass to get the entire dose.

Not all drugs can be crushed, so it is important to speak with your pharmacist if you are planning to crush any of your other medications.


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