Chrome 2001
.
Aetna Intelihealth InteliHealth Aetna Intelihealth Aetna Intelihealth
 
     
.
. .
.
Home
Health Commentaries
InteliHealth Dental
Drug Resource Center
Ask the Expert
Interactive Tools
Todays News
InteliHealth Policies
Site Map

   Advertisement
Mindbloom Ad .
Diseases & Conditions Healthy Lifestyle Your Health Look It Up
High Blood Pressure High Blood Pressure
.
High Blood Pressure
8315
High Blood Pressure
An article in The Lancet Oncology says that angiotensin receptor blockers, a family of drugs used to treat high blood pressure, increases the risk of cancer. I take 16 mg. of candesartan each day. Should I quit using it?
An article in The Lancet Oncology says that angiotensin receptor blockers, a family of drugs used to treat high blood pressure, increases the risk of cancer. I take 16 mg. of candesartan each day. Should I quit using it?
htmASKTHEDOCcandesartan
The article raised concern about a possible association of new cancer diagnoses in people taking angiotensin receptor blockers. These include candesartan and telmisartan. The drug is prescribed to treat high blood pressure and heart failure.
1376662
InteliHealth
2010-10-07
t
Marc Garnick, M.D.
2012-10-07
.
Ask The Expert
Harvard Medical School
.
Image of a cadeusus
. .
General Medical Questions
.
Q: An article in The Lancet Oncology says that angiotensin receptor blockers, a family of drugs used to treat high blood pressure, increases the risk of cancer. I take 16 mg. of candesartan each day. Should I quit using it?
.
.
.
The Trusted Source
.
.

Dr. Garnick is an internationally renowned expert in medical oncology and urologic cancer, with a special emphasis on prostate cancer. He is a Clinical Professor of Medicine at Harvard Medical School and maintains an active oncology practice at Beth Israel Deaconess Medical Center. Dr. Garnick serves as Editor in Chief of Perspectives on Prostate Diseases, an annual report from Harvard Health Publications.

.
.
October 07, 2010
.
A:

The article raised concern about a possible association of new cancer diagnoses in people taking angiotensin receptor blockers. These include candesartan and telmisartan. The drug is prescribed to treat high blood pressure and heart failure.

The article combined data from many studies to evaluate the possible relationship between cancer and people taking these drugs. The finding, yet to be confirmed, was that there seemed to be an increase in new cancers, especially lung cancer, in people taking this class of drugs.

Much of the data compared people taking the drugs to those who were taking a placebo (a fake or sugar pill) or another type of blocker. Most of the studies included people who were taking telmisartan. And most of the new cancer data were from studies that used telmisartan, not candesartan.

As with any new study, we must take the research seriously, especially given the adverse effect -- in this case, an increase in cancer.

However, as with any new study, we must be cautious to not over-interpret the results. This new information was collected more or less in a random fashion. The goal of the original studies was not to look for a cancer connection. Researchers just found this possible link after the fact. This means we don't know key information about the people who developed cancer. Such factors would include a family history of cancer, whether they smoked or took drugs or alcohol, whether they were physically active, their body type, etc.

The problem with studies like this is that it may be years before we know whether the data is true or not.

My best advice is to talk to the doctor who prescribed your candesartan. If this is the only drug that is likely to work to treat your condition, I would continue taking it. If, however, there are other drugs (non angiotensin receptor blockers) that could work, I would consider a possible switch.

.
.
InteliHealth
.
Ask A Question
.
.
InteliHealth
Do You Have A Question?
.
. . .
.
Ask The Expert Archives
Topics
.
InteliHealth
.
InteliHealth

   
4581, 8466, 29595,
cancer,drug
29595
.
.  
This website is certified by Health On the Net Foundation. Click to verify.
.
Chrome 2001
Chrome 2001