| Biguanides | Generic name | Brand name | metformin | Glucophage Glucophage XR Glycon
| |
| Long-acting pancreas stimulators (sulfonylureas) | Generic name | Brand name | acetohexamide | Dymelor | chlorpropamide | Diabinese | gliclazide | Diamicron, Diamicron MR | glimepiride | Amaryl | glipizide | Glucotrol Glucotrol XL | glyburide | Micronase DiaBeta Glynase PresTab Euglucon | tolazamide | Tolinase | tolbutamide | Orinase Tol-Tab | |
| GLP-1 agents | Generic name | Brand name | exentatide | Byetta
| sitagliptin | Januvia | |
| Combination pills | Generic name | Brand name | metformin plus glyburide | Glucovance | glipizide plus metformin | Metaglip | rosiglitazone plus metformin | Avandamet | pioglitazone plus metformin | Actoplus Met | rosiglitazone plus glimepiride | Avandaryl | pioglitazone plus glimepiride | Duetact | sitagliptin plus metformin | Janumet | |
| Rapid-acting insulins | Generic name | Brand name | Onset of effect (hours) | Peak effect (hours) | Duration of effect (hours) | aspart | Novolog | ¼ | ¾ | 3 to 5 | glulisine | Apidra | 0 to ¼ | ¾ to 2 | 2 to 4 | lispro | Humalog | 0 to ¼ | ½ to 1½ | 6 to 8 | regular insulin | Humulin R Novolin R Regular Iletin I Regular Iletin II Regular Iletin II (Concentrated) Regular Purified Pork Insulin Velosulin Human BR | ½ to 1 | 2 to 4 | 6 to 8 | |
| Intermediate-acting insulins | Generic name | Brand name | Onset of effect (hours) | Peak effect (hours) | Duration of effect (hours) | NPH ("isophane") insulin | Humulin N Novolin N NPH Iletin I NPH Iletin II NPH-N | 1 to 1½ | 4 to 12 | 24 | lente insulin | Humulin L Lente Iletin I Lente Iletin II Lente L Novolin L | 1 to 2½ | 7 to 15 | 24 | |
| Long-acting insulins | Generic name | Brand name | Onset of effect (hours) | Peak effect (hours) | Duration of effect (hours) | ultralente | Humulin U Ultralente | 4 to 8 | 10 to 30 | More than 36 | detemir | Levemir | Continuous, steady level once you are on a stable daily dose | glargine | Lantus | Continuous, steady level once you are on a stable daily dose | |
| Mixed insulins | Generic name | Brand name | Onset of effect (hours) | Peak effect (hours) | Duration of effect (hours) | 50% NPH, 50% regular insulin | Humulin 50/50 | ½ to 1 | 4 to 8 | 18 to 24 | 70% NPH, 30% regular insulin | Humulin 70/30 Novolin 70/30 | ½ to 1 | 4 to 8 | 18 to 24 | |
Last updated July 22, 2010
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