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General Medical Questions
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Q: I have type 2 diabetes. I just had a prednisone shot in my knee. My blood sugar shot up to near 300. How long will this shot effect my blood sugar levels?
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The Trusted Source
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Mary Pickett, M.D.

Mary Pickett, M.D., is an Associate professor at Oregon Health & Science University where she is a primary care doctor for adults. She supervises and educates residents in the field of Internal Medicine, for outpatient and hospital care. She is a Lecturer for Harvard Medical School and a Senior Medical Editor for Harvard Health Publications.

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October 07, 2009
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A:

It is common for a corticosteroid injected into a joint to raise blood sugar for several days. Common injected corticosteroid medicines are triamcinolone (Aristocort or Kenalog) and methylprednisolone (Depo-Medrol).

Your doctor may not feel it is important to increase your diabetes medicines in reaction to this short-term change in your sugar control. Drink plenty of fluids so you remain well hydrated anytime your glucose levels are elevated.

If your glucose levels remain elevated for longer than 3 to 5 days, call your doctor. There is a small risk of infection after an injection into a joint, so report worsened joint pain or fever to your doctor.

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