Chrome 2001
.
The Trusted Source InteliHealth Aetna InteliHealth Aetna InteliHealth
Enter Drug Name . Enter Search Term
     
. .
. .
.
Home
Health Commentaries
InteliHealth Dental
Drug Resource Center
Ask the Expert
Interactive Tools

InteliHealth Policies
Site Map
Diseases & Conditions Healthy Lifestyle Your Health Look It Up
Health News Health News
.
Associated Press

Schering And Organon Developing Male Hormonal Contraceptive For U.S. And European Markets
November 21, 2002

FRANKFURT, Germany (AP) -- Pharmaceutical companies Schering AG and Organon said Thursday they aim to produce a marketable hormone contraceptive for men in five to seven years -- a goal that has stumped researchers for decades.

Trials for the product -- a long-term implant accompanied by an injection every three months -- will start next year, with the goal of marketing the product in the United States and Europe, the companies said.

"A hormonal form of fertility control for men would expand the choice of contraceptives for couples," Werner-Karl Raff, head of Schering's contraceptives division, said in a written statement. "We are optimistic that we can fill this gap in the future."

The implant would contain a hormone belonging to the progestin class, which would stop production of both sperm and the male hormone testosterone. Injections of a testosterone derivative would replace natural levels of the hormone, necessary for normal sexual functioning.

Organon, which bases its top management in Westland, New Jersey, but has its biggest facilities in Ostend, the Netherlands, would make the implant - a version of its already existing Implanon female birth control implant.

Berlin-based Schering would produce the injected testosterone derivative, known as testosterone undecanoate. The companies could not say how much the product would cost, how much they expected to earn from it, or how it would be marketed.

Schering spokeswoman Astrid Forster acknowledged that some might find the delivery method inconvenient, requiring visits to the doctor to have the implant inserted in the upper arm and to have the injections.

In trials funded by Organon and done by University of Edinburgh researchers of 66 men in Scotland and China, the drug stopped sperm production but produced minor side effects such as mood swings, weight gain and increased appetite.

Researchers in Australia also say they have successfully tested a progestin-testosterone combination.

Schering and Organon said they would use the development period to try to come up with a more convenient way to administer the doses. "Of course, we know it's not very comfortable," she said. "But these are the first steps, and we will try to learn from this project and optimize it for the future."

The implant was intended to last a year during the trial phase, the companies said.

Researchers say that most major pharmaceutical companies have not shown much interest in developing and marketing male contraceptives. They also cite a biological obstacle - female birth control pills must stop the production of one egg a month, as opposed to millions of sperm produced every day.

But Schering's Forster said that the number of men who have had vasectomies suggests there would be demand for the product -- which would be easily reversible.

She said that the tests would provide more information, but that it was expected that fertility would return in three months after ceasing use.

Copyright 2002 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

.
InteliHealth
. . . .
.
More News
InteliHealth .
.
Top News
General Health
This Week In Health
Addiction
Allergy
Alzheimer's
Asthma
Arthritis
Babies
Breast Cancer
Cancer
Caregiving
Cervical Cancer
Children's Health
Cholesterol
Complementary & Alternative Medicine
Dental / Oral Health
Depression
Diabetes
Ear, Nose And Throat
Eyes
Family Health
Fitness
Headache
Heart Health
HIV / AIDS
Infectious Diseases
Lung Cancer
Medications
Men's Health
Mental Health
Nutrition News
Multiple Sclerosis
Nutrition Guide
Parkinson's
Pregnancy
Prevention
Prostate Cancer
Senior Health
Sexual / Reproductive Health
Sleep
Tobacco Cessation
STDs
Stress Reduction
Stroke
Weight Management
Today In Health History
Women's Health
Workplace Health
.
.
.
.
InteliHealth

   
.
.   HONcode
.
Chrome 2001
Chrome 2001